A data-matrix (DM)-technology approach in cell biology is implemented as an efficient method for the multiparameter monitoring of cell cultures. The proposed method takes advantage of the know-how developed for fault tolerance in digital information technology by measuring the amount of errors induced by intervening cells upon checking a DM code placed behind them. It gives continuous access to several quantitative parameters of the observed culture, such as cell coverage, mean size, viability, and transfection efficiency.

Data-Matrix Technology for Multiparameter Monitoring of Cell Cultures

Marianna Barbalinardo;Denis Gentili;Francesco Valle
;
Marco Brucale;Manuela Melucci;Ana I. Borrachero-Conejo;Emanuela Saracino;Valentina Benfenati;GRECO, PAOLO;FOSCHI, GIULIA;
2018

Abstract

A data-matrix (DM)-technology approach in cell biology is implemented as an efficient method for the multiparameter monitoring of cell cultures. The proposed method takes advantage of the know-how developed for fault tolerance in digital information technology by measuring the amount of errors induced by intervening cells upon checking a DM code placed behind them. It gives continuous access to several quantitative parameters of the observed culture, such as cell coverage, mean size, viability, and transfection efficiency.
Marianna Barbalinardo, Denis Gentili, Francesca Lazzarotto, Francesco Valle, Marco Brucale, Manuela Melucci, Laura Favaretto, Massimo Zambianchi, Ana I. Borrachero-Conejo, Emanuela Saracino, Valentina Benfenati, Davide Natalini, Paolo Greco, Maria Giovanna Di Carlo, Giulia Foschi, and Massimiliano Cavallini
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/659952
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