Uric acid and early prevention of vascular diseases: Women under the looking glass

The identification of new or emerging risk factors for cardiovascular disease is a non-stop challenge aimed at the early prevention of cardiovascular (CV) damage before is too late. Uric acid is the end-product of purine metabolism in superior primates and the Dalmatian dog and its deposition as sodium monourate crystals is responsible for gout and its complications. However, the possibility of damaging the articular tissue is only one of the possible negative effects of uric acid whose plasma concentration has been closely correlated with the incidence of CV and metabolic diseases with a significant increase in the risk of major CV events regardless of the presence of gout.