Attenzione: i dati modificati non sono ancora stati salvati. Per confermare inserimenti o cancellazioni di voci è necessario confermare con il tasto SALVA/INSERISCI in fondo alla pagina
CRIS Current Research Information System
OBJECTIVE: Carotid intima-media thickness (cIMT) is a surrogate marker of
subclinical atherosclerosis and it is able to predict both coronary and cerebral
vascular events. No data exist on the association between cIMT and non valvular
atrial fibrillation (NVAF) type. We conduct this study with the aim to analyze
the association between abnormal cIMT and NVAF type.
METHODS: A cross-sectional study of the "Atrial fibrillation Registry for
Ankle-brachial index Prevalence Assessment-Collaborative Italian Study
(ARAPACIS)" has been performed. Among 2027 patients enrolled in the ARAPACIS, 673
patients, who underwent carotid ultrasound examination to assess cIMT, were
included in the study.
RESULTS: Among the entire population, 478 patients (71%) had cIMT > 0.90 mm.
Patients with an abnormal cIMT (>0.90 mm) were significantly older and more
likely hypertensive, diabetic and with a previous history of stroke than those
with normal cIMT (≤0.90 mm). These patients had more permanent/persistent NVAF
and CHA2DS2-VASc score ≥ 2 (p < 0.0001) compared to those with cIMT <0.90 mm.
Excluding all patients affected by previous cardiovascular disease, logistic
regression analysis showed that independent predictors of abnormal cIMT were: age
class 65-74 yrs. (p < 0.001), age class ≥75 yrs. (p < 0.001), arterial
hypertension (p < 0.001), calcium-channel blockers use (p < 0.001) and
persistent/permanent NVAF (p = 0.001).
CONCLUSION: Our findings show a high prevalence of abnormal cIMT in NVAF
patients, reinforcing the concept that NVAF and systemic atherosclerosis are
closely associated. Abnormal cIMT was particularly evident in
persistent/permanent NVAF suggesting a more elevated atherosclerotic burden in
patients with long-standing NVAF.
TRIAL REGISTRATION: http://clinicaltrials.gov/ct2/show/NCT01161251.
Proietti M, C.C. (2015). Relationship between carotid intima-media thickness and non valvular atrial fibrillation type. ATHEROSCLEROSIS, 238(2), 350-355 [10.1016/j.atherosclerosis.2014.12.022].
Relationship between carotid intima-media thickness and non valvular atrial fibrillation type
OBJECTIVE: Carotid intima-media thickness (cIMT) is a surrogate marker of
subclinical atherosclerosis and it is able to predict both coronary and cerebral
vascular events. No data exist on the association between cIMT and non valvular
atrial fibrillation (NVAF) type. We conduct this study with the aim to analyze
the association between abnormal cIMT and NVAF type.
METHODS: A cross-sectional study of the "Atrial fibrillation Registry for
Ankle-brachial index Prevalence Assessment-Collaborative Italian Study
(ARAPACIS)" has been performed. Among 2027 patients enrolled in the ARAPACIS, 673
patients, who underwent carotid ultrasound examination to assess cIMT, were
included in the study.
RESULTS: Among the entire population, 478 patients (71%) had cIMT > 0.90 mm.
Patients with an abnormal cIMT (>0.90 mm) were significantly older and more
likely hypertensive, diabetic and with a previous history of stroke than those
with normal cIMT (≤0.90 mm). These patients had more permanent/persistent NVAF
and CHA2DS2-VASc score ≥ 2 (p < 0.0001) compared to those with cIMT <0.90 mm.
Excluding all patients affected by previous cardiovascular disease, logistic
regression analysis showed that independent predictors of abnormal cIMT were: age
class 65-74 yrs. (p < 0.001), age class ≥75 yrs. (p < 0.001), arterial
hypertension (p < 0.001), calcium-channel blockers use (p < 0.001) and
persistent/permanent NVAF (p = 0.001).
CONCLUSION: Our findings show a high prevalence of abnormal cIMT in NVAF
patients, reinforcing the concept that NVAF and systemic atherosclerosis are
closely associated. Abnormal cIMT was particularly evident in
persistent/permanent NVAF suggesting a more elevated atherosclerotic burden in
patients with long-standing NVAF.
TRIAL REGISTRATION: http://clinicaltrials.gov/ct2/show/NCT01161251.
Proietti M, C.C. (2015). Relationship between carotid intima-media thickness and non valvular atrial fibrillation type. ATHEROSCLEROSIS, 238(2), 350-355 [10.1016/j.atherosclerosis.2014.12.022].
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/654226
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
Citazioni
11
31
31
social impact
Conferma cancellazione
Sei sicuro che questo prodotto debba essere cancellato?
simulazione ASN
Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande.
La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 589/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.