HSP70, HSP27 and TNF-a were measured by immunoblotting in samples of pathological and healthy cutaneous and gland tissues (20 dogs of different ages and sex). HSP70 and HSP27 expressions are respectively characterized by a significant increase (p<0.01) and decrease in pathological tissues compared to healthy ones. Preliminary detections on TNF-a don’t show significant differences. This work underlines the importance of HSPs and cytokines and the close relationships with several pathological conditions. Further investigations will be carry out to obtain valid markers for neoplasm in dogs tissues
Monari M., Foschi J., Bichi Ruspoli Forteguerri E., Valgimigli S., Zanatta M., Capitani O., et al. (2009). Evaluation of HSP70, 27 and TNF-a expression in different canine cutaneous and gland diseases.
Evaluation of HSP70, 27 and TNF-a expression in different canine cutaneous and gland diseases
MONARI, MARTA;FOSCHI, JURGEN;BICHI RUSPOLI FORTEGUERRI, ELENA;VALGIMIGLI, SIMOND;ZANATTA, MARCO;CAPITANI, OMBRETTA;SERRAZANETTI, GIAN PAOLO
2009
Abstract
HSP70, HSP27 and TNF-a were measured by immunoblotting in samples of pathological and healthy cutaneous and gland tissues (20 dogs of different ages and sex). HSP70 and HSP27 expressions are respectively characterized by a significant increase (p<0.01) and decrease in pathological tissues compared to healthy ones. Preliminary detections on TNF-a don’t show significant differences. This work underlines the importance of HSPs and cytokines and the close relationships with several pathological conditions. Further investigations will be carry out to obtain valid markers for neoplasm in dogs tissuesI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
