Multi-layer inkjet printing is applied to prepare microchips that consist of up to eight three-electrode sensors comprising a carbon nanotube (CNT) working electrode, a silver/silver chloride quasi-reference electrode and a CNT counter electrode. Optionally, the sensors contain micro-wells to measure sample volumes as small as 50 μL. The implementation of inkjet printing allows the flexible design and highly reproducible fabrication of batches of various electrode shapes and dimensions. The usage of CNTs as standalone working electrodes results in electroanalytical sensors with reliable and superior electrochemical response compared to tested commercial carbon paste electrodes. The sensors can be used at least up to 20 times, e.g., based on an immunoassay based strategy, or in a disposable way, e.g., when measuring in complex matrices such as blood. A gold ink is applied as alternative working electrode material. The printed sensors can be used with compact multichannel potentiostats that are suitable for point-of-care diagnostics.
Point-of-care diagnostics with inkjet-printed microchips / Lesch, A.; Jović, M.; Baudoz, M.; Zhu, Y.; Tacchini, P.; Gumy, F.; Girault, H.H.. - In: ECS TRANSACTIONS. - ISSN 1938-5862. - ELETTRONICO. - 77:7(2017), pp. 73-84. (Intervento presentato al convegno Symposium on Solid-State Electronics and Photonics in Biology and Medicine 4 - 231st ECS Meeting 2017 tenutosi a USA nel 2017) [10.1149/07707.0073ecst].
Point-of-care diagnostics with inkjet-printed microchips
Lesch, A.;
2017
Abstract
Multi-layer inkjet printing is applied to prepare microchips that consist of up to eight three-electrode sensors comprising a carbon nanotube (CNT) working electrode, a silver/silver chloride quasi-reference electrode and a CNT counter electrode. Optionally, the sensors contain micro-wells to measure sample volumes as small as 50 μL. The implementation of inkjet printing allows the flexible design and highly reproducible fabrication of batches of various electrode shapes and dimensions. The usage of CNTs as standalone working electrodes results in electroanalytical sensors with reliable and superior electrochemical response compared to tested commercial carbon paste electrodes. The sensors can be used at least up to 20 times, e.g., based on an immunoassay based strategy, or in a disposable way, e.g., when measuring in complex matrices such as blood. A gold ink is applied as alternative working electrode material. The printed sensors can be used with compact multichannel potentiostats that are suitable for point-of-care diagnostics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
