The [Ni(II)]-catalyzed cross-coupling of aryl boronic acids and allenoates is documented. The high regio- and stereoselectivity of the process enables a wide range of -aryl -unsaturated esters to be prepared in good to excellent yields (up to 95%) and high E:Z-selectivity. Additionally, [3+2]-cascade sequence was observed when the 2-formyl boronic acid 2p was employed.
Yang Liu, M.D. (2018). Regio and Stereoselective Nickel Catalyzed Coupling of Boronic Acids with Allenoates. SYNTHESIS, 50, 3187-3196 [10.1055/s-0037-1610023].
Regio and Stereoselective Nickel Catalyzed Coupling of Boronic Acids with Allenoates
LIU, YANGMembro del Collaboration Group
;DAKA, MARIOMembro del Collaboration Group
;Marco Bandini
Project Administration
2018
Abstract
The [Ni(II)]-catalyzed cross-coupling of aryl boronic acids and allenoates is documented. The high regio- and stereoselectivity of the process enables a wide range of -aryl -unsaturated esters to be prepared in good to excellent yields (up to 95%) and high E:Z-selectivity. Additionally, [3+2]-cascade sequence was observed when the 2-formyl boronic acid 2p was employed.File in questo prodotto:
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