Three-dimensional (3D) visualisation of microscopic structures provides useful information about their configuration and the spatial (hence functional) relationship between different components in tissues. This paper describes 3D dynamic reconstructions of the pre-lymphatic labyrinth in two cases of "normal" breast core biopsies and one case of pseudoangiomatous stromal hyperplasia. Direct anastomoses between pre-lymphatic channels and true lymphatics of the breast were demonstrated. It is concluded that pre-lymphatics are a way of communication between breast epithelial/stromal structures and the main lymphatic system. The present findings suggest that the existence of prelymphatics has to be taken in consideration in the intramammary spread of malignant tumours.

Asioli S., Eusebi V., Gaetano L., Losi L., Bussolati G. (2008). The pre-lymphatic pathway, the rooths of the lymphatic system in breast tissue: a 3D study. VIRCHOWS ARCHIV, 453(4), 401-406 [10.1007/s00428-008-0657-y].

The pre-lymphatic pathway, the rooths of the lymphatic system in breast tissue: a 3D study

ASIOLI, SOFIA;EUSEBI, VINCENZO;
2008

Abstract

Three-dimensional (3D) visualisation of microscopic structures provides useful information about their configuration and the spatial (hence functional) relationship between different components in tissues. This paper describes 3D dynamic reconstructions of the pre-lymphatic labyrinth in two cases of "normal" breast core biopsies and one case of pseudoangiomatous stromal hyperplasia. Direct anastomoses between pre-lymphatic channels and true lymphatics of the breast were demonstrated. It is concluded that pre-lymphatics are a way of communication between breast epithelial/stromal structures and the main lymphatic system. The present findings suggest that the existence of prelymphatics has to be taken in consideration in the intramammary spread of malignant tumours.
2008
Asioli S., Eusebi V., Gaetano L., Losi L., Bussolati G. (2008). The pre-lymphatic pathway, the rooths of the lymphatic system in breast tissue: a 3D study. VIRCHOWS ARCHIV, 453(4), 401-406 [10.1007/s00428-008-0657-y].
Asioli S.; Eusebi V.; Gaetano L.; Losi L.; Bussolati G.
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/64241
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 10
social impact