To assess the risk of major congenital malformations (MCMs) in association with maternal use of valproic acid (VPA) in monotherapy or adjunctive therapy, and its relationship with dose.
Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study / Tomson, Torbjörn; Battino, Dina; Bonizzoni, Erminio; Craig, John; Lindhout, Dick; Perucca, Emilio; Sabers, Anne; Thomas, Sanjeev V; Vajda, Frank; for the EURAP Study Group; Bisulli, Francesca; Tinuper, Paolo. - In: NEUROLOGY. - ISSN 0028-3878. - STAMPA. - 85:10(2015), pp. 866-872. [10.1212/WNL.0000000000001772]
Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study
Bisulli, FrancescaMembro del Collaboration Group
;Tinuper, PaoloMembro del Collaboration Group
2015
Abstract
To assess the risk of major congenital malformations (MCMs) in association with maternal use of valproic acid (VPA) in monotherapy or adjunctive therapy, and its relationship with dose.File in questo prodotto:
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