The dipeptide Boc-L-Phe-D-Oxd-OBn spontaneously forms fibers consisting of parallel infinite linear chains arising from single intermolecular N-H…O=C hydrogen bonds, as demonstrated by IR spectroscopy, X-ray diffraction, and solid-state NMR. SEM observations show that the thickness and the width of the filamentous material are almost constant. This is the absolute borderline case of a parallel beta-sheet structure.
G. Angelici, G. Falini, H.-J. Hofmann, D.Huster, M. Monari, C. Tomasini (2008). A fiber-like peptide material stabilized by single intermolecular hydrogen bonds. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 47, 8075-8078 [10.1002/anie.200802587].
A fiber-like peptide material stabilized by single intermolecular hydrogen bonds
ANGELICI, GAETANO;FALINI, GIUSEPPE;MONARI, MAGDA;TOMASINI, CLAUDIA
2008
Abstract
The dipeptide Boc-L-Phe-D-Oxd-OBn spontaneously forms fibers consisting of parallel infinite linear chains arising from single intermolecular N-H…O=C hydrogen bonds, as demonstrated by IR spectroscopy, X-ray diffraction, and solid-state NMR. SEM observations show that the thickness and the width of the filamentous material are almost constant. This is the absolute borderline case of a parallel beta-sheet structure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
