Prosthetic joint infection (PJI) is among the most-severe complications of a total joint arthroplasty. Identification of the causal organism is of paramount importance for successful treatment, and sonication of implants may aid in this identification. Dithiothreitol (DTT) treatment has been proposed as an alternative to sonication to improve diagnosis, reduce costs, and improve reliability of the procedure, but its efficacy remains poorly characterized.
Sambri, A., Cadossi, M., Giannini, S., Pignatti, G., Marcacci, M., Neri, M.P., et al. (2018). Is Treatment With Dithiothreitol More Effective Than Sonication for the Diagnosis of Prosthetic Joint Infection?. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 476(1), 137-145 [10.1007/s11999.0000000000000060].
Is Treatment With Dithiothreitol More Effective Than Sonication for the Diagnosis of Prosthetic Joint Infection?
Sambri, Andrea;Cadossi, Matteo;Giannini, Sandro;Pignatti, Giovanni;Marcacci, Maurilio;Neri, Maria Pia;Storni, Elisa;Gamberini, Simonetta;Naldi, Susanna;Fantini, Michela;Donati, Davide;Sambri, Vittorio
2018
Abstract
Prosthetic joint infection (PJI) is among the most-severe complications of a total joint arthroplasty. Identification of the causal organism is of paramount importance for successful treatment, and sonication of implants may aid in this identification. Dithiothreitol (DTT) treatment has been proposed as an alternative to sonication to improve diagnosis, reduce costs, and improve reliability of the procedure, but its efficacy remains poorly characterized.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
