The optimal threshold for neonatal platelet transfusions in sick newborns is still uncertain. We report a congenital cytomegalovirus (CMV) infection in a premature neonate with severe thrombocytopenia who subsequently presented with necrotizing enterocolitis and intestinal bleeding. The baby recovered after platelet transfusions were discontinued and the therapy was switched from intravenous ganciclovir to oral valganciclovir. We discuss both measures, speculating on the key role of platelet transfusions.
Persistent intestinal bleeding due to severe CMV-related thrombocytopenia in a preterm newborn / Berardi A; Spaggiari E; Cattelani C; Roversi MF; Pecorari M; Lazzarotto T; Ferrari F.. - In: THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. - ISSN 1476-7058. - STAMPA. - 31:9(2018), pp. 1246-1249. [10.1080/14767058.2017.1312331]
Persistent intestinal bleeding due to severe CMV-related thrombocytopenia in a preterm newborn
Lazzarotto TWriting – Review & Editing
;
2018
Abstract
The optimal threshold for neonatal platelet transfusions in sick newborns is still uncertain. We report a congenital cytomegalovirus (CMV) infection in a premature neonate with severe thrombocytopenia who subsequently presented with necrotizing enterocolitis and intestinal bleeding. The baby recovered after platelet transfusions were discontinued and the therapy was switched from intravenous ganciclovir to oral valganciclovir. We discuss both measures, speculating on the key role of platelet transfusions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
