Background: Sodium prescription in patients with intradialytic hypotension remains a challenge for the attending nephrologist, as it increases dialysate conductivity in hypotension-prone patients, thereby adding to dietary sodium levels. Methods: New sodium prescription strategies are now available, including the use of a mathematical model to compute the sodium mass to be removed during dialysis as a physiological controller. Results: This review describes the sodium load of patients with end-stage renal disease on chronic hemodialysis (HD) and discusses 2 strategies to remove excess sodium in patients prone to intradialytic hypotension, namely, Profiled HD and the hemodiafiltration Aequilibrium System. Conclusion: The Profiled HD and Aequilibrium System trial both proved effective in counteracting intradialytic hypotension.

Sodium Prescription in the Prevention of Intradialytic Hypotension: New Insights into an Old Concept

Donati, Gabriele;Ursino, Mauro;Spazzoli, Alessandra;Schillaci, Roberto;Conte, Diletta;Angeletti, Andrea;Croci Chiocchini, Anna Laura;Capelli, Irene;Baraldi, Olga;La Manna, Gaetano
2018

Abstract

Background: Sodium prescription in patients with intradialytic hypotension remains a challenge for the attending nephrologist, as it increases dialysate conductivity in hypotension-prone patients, thereby adding to dietary sodium levels. Methods: New sodium prescription strategies are now available, including the use of a mathematical model to compute the sodium mass to be removed during dialysis as a physiological controller. Results: This review describes the sodium load of patients with end-stage renal disease on chronic hemodialysis (HD) and discusses 2 strategies to remove excess sodium in patients prone to intradialytic hypotension, namely, Profiled HD and the hemodiafiltration Aequilibrium System. Conclusion: The Profiled HD and Aequilibrium System trial both proved effective in counteracting intradialytic hypotension.
2018
Donati, Gabriele; Ursino, Mauro; Spazzoli, Alessandra; Natali, Nicolã²; Schillaci, Roberto; Conte, Diletta; Angeletti, Andrea; Croci Chiocchini, Anna Laura; Capelli, Irene; Baraldi, Olga; La Manna, Gaetano
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/614459
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