Background: The rising number of patients on waiting lists for kidney transplant and the shortage of available organs has intensified efforts to increase the number of potential donors. Material/Methods: This study investigated changes in clinical parameters among potential deceased donors in the 15-year period between 1999 and 2013 and their impact on transplantation procedure and outcomes. A total of 1634 potential deceased donors were examined and divided into 2 groups: 707 of them identified from 1999 to 2005 (Group A), and 927 from 2006 to 2013 (Group B). Results: The comparison between the potential donors in Group A vs. Group B revealed an increase over time in donor age (54.6±17.2 vs. 58.8±16.3, p<0.001), a reduction in the percentage of standard donors (52.3% vs. 39.8%, p<0.001), a broader utilization of organs from expanded criteria donors, and a greater number of comorbidi-ties, particularly cardiovascular disease and dyslipidemia. However, renal function parameters and the bioptic scores did not change significantly over the years. Conclusions: These results suggest the usefulness of strategies to increase the number of potential donors suitable for organ donation, especially among elderly and marginal donors.

Fifteen-year analysis of deceased kidney donation: A single transplant center experience in a region of northern Italy

Cuna, Vania;Comai, Giorgia;Cappuccilli, Maria;Baraldi, Olga;Capelli, Irene;DE LIBERALI, MATTEO;Gasperoni, Lorenzo;Conte, Diletta;Ravaioli, Matteo;Pinna, Antonio D.;La Manna, Gaetano
2017

Abstract

Background: The rising number of patients on waiting lists for kidney transplant and the shortage of available organs has intensified efforts to increase the number of potential donors. Material/Methods: This study investigated changes in clinical parameters among potential deceased donors in the 15-year period between 1999 and 2013 and their impact on transplantation procedure and outcomes. A total of 1634 potential deceased donors were examined and divided into 2 groups: 707 of them identified from 1999 to 2005 (Group A), and 927 from 2006 to 2013 (Group B). Results: The comparison between the potential donors in Group A vs. Group B revealed an increase over time in donor age (54.6±17.2 vs. 58.8±16.3, p<0.001), a reduction in the percentage of standard donors (52.3% vs. 39.8%, p<0.001), a broader utilization of organs from expanded criteria donors, and a greater number of comorbidi-ties, particularly cardiovascular disease and dyslipidemia. However, renal function parameters and the bioptic scores did not change significantly over the years. Conclusions: These results suggest the usefulness of strategies to increase the number of potential donors suitable for organ donation, especially among elderly and marginal donors.
MEDICAL SCIENCE MONITOR
Cuna, Vania; Comai, Giorgia; Cappuccilli, Maria; Baraldi, Olga; Capelli, Irene; De Liberali, Matteo; Gasperoni, Lorenzo; Conte, Diletta; Ravaioli, Matteo; Pinna, Antonio D.; La Manna, Gaetano
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/613054
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