Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are emerging problems in several countries. These infections require long and expensive treatment regimens. Recently, 2 new drugs, bedaquiline and delamanid, have been approved in several countries for use in adults with severe, difficult-to-treat MDR-TB, and it has been suggested that they could also be administered to children with MDR-TB and limited treatment options. However, no study has been completed on their efficacy.
Titolo: | Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis: A case report and review of the literature |
Autore/i: | Esposito, Susanna; Bosis, Samantha; TADOLINI, MARINA; Bianchini, Sonia; Migliori, Giovanni Battista; Principi, Nicola |
Autore/i Unibo: | |
Anno: | 2016 |
Rivista: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1097/MD.0000000000005347 |
Abstract: | Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are emerging problems in several countries. These infections require long and expensive treatment regimens. Recently, 2 new drugs, bedaquiline and delamanid, have been approved in several countries for use in adults with severe, difficult-to-treat MDR-TB, and it has been suggested that they could also be administered to children with MDR-TB and limited treatment options. However, no study has been completed on their efficacy. |
Data stato definitivo: | 2017-06-13T14:30:40Z |
Appare nelle tipologie: | 1.01 Articolo in rivista |
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