the presence and inducibility of CYP enzymes belonging to the family 1 (CYP 1A1, 1A2 and 1B!) and AhR have been studied in liver, lung, kidney and heart of control and beta-naphtoflavone (betaNF)-treated pigs. Segments of so far undescribed genes for porcine CYP 1A1, 1A2, 1B1 and Ahr were identified by RT_PCR and their sequences found to be higly homologous to those of the corresponding human genes. Our results demonstrated a differential expression and regulation of the AhR-mediated CYP genes in liver, lung, kidney and heart of the pig-naphtoflavone.

Chirulli V., Marvasi L., Zaghini A., Fiorio R., Longo V., Grvasi P.G. (2007). Inducibility of AhR-regulated CYP genes by beta-naphtoflavone in the liver, lung, kidney and heart of the pig. TOXICOLOGY, 240, 25-37 [10.1016/j.tox.2007.07.015].

Inducibility of AhR-regulated CYP genes by beta-naphtoflavone in the liver, lung, kidney and heart of the pig

MARVASI, LUIGI;ZAGHINI, ANNA;
2007

Abstract

the presence and inducibility of CYP enzymes belonging to the family 1 (CYP 1A1, 1A2 and 1B!) and AhR have been studied in liver, lung, kidney and heart of control and beta-naphtoflavone (betaNF)-treated pigs. Segments of so far undescribed genes for porcine CYP 1A1, 1A2, 1B1 and Ahr were identified by RT_PCR and their sequences found to be higly homologous to those of the corresponding human genes. Our results demonstrated a differential expression and regulation of the AhR-mediated CYP genes in liver, lung, kidney and heart of the pig-naphtoflavone.
2007
Chirulli V., Marvasi L., Zaghini A., Fiorio R., Longo V., Grvasi P.G. (2007). Inducibility of AhR-regulated CYP genes by beta-naphtoflavone in the liver, lung, kidney and heart of the pig. TOXICOLOGY, 240, 25-37 [10.1016/j.tox.2007.07.015].
Chirulli V.; Marvasi L.; Zaghini A.; Fiorio R.; Longo V.; Grvasi P.G.
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/59548
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 33
  • ???jsp.display-item.citation.isi??? 34
social impact