Different components of the immune system, including innate and adaptive immunity (T effector lymphocytes and T regulatory lymphocytes - TREGs) may be involved in the development of hypertension, vascular injury and inflammation. However, no data are presently available in humans about possible relationships between T-lymphocyte subtypes and microvascular oxidative stress. Our objective was to investigate possible relationships between T-lymphocyte subtypes and systemic and microvascular oxidative stress in a population of normotensive subjects and hypertensive patients.
Relationship between different subpopulations of circulating CD4+ T lymphocytes and microvascular or systemic oxidative stress in humans / De Ciuceis, Carolina; Agabiti-Rosei, Claudia; Rossini, Claudia; Airò, Paolo; Scarsi, Mirko; Tincani, Angela; Tiberio, Guido Alberto Massimo; Piantoni, Silvia; Porteri, Enzo; Solaini, Leonardo; Duse, Sarah; Semeraro, Francesco; Petroboni, Beatrice; Mori, Luigi; Castellano, Maurizio; Gavazzi, Alice; Agabiti-Rosei, Enrico; Rizzoni, Damiano. - In: BLOOD PRESSURE. - ISSN 0803-7051. - ELETTRONICO. - 15:(2017), pp. 1-9. [10.1080/08037051.2017.1292395]
Relationship between different subpopulations of circulating CD4+ T lymphocytes and microvascular or systemic oxidative stress in humans
SOLAINI, LEONARDO;
2017
Abstract
Different components of the immune system, including innate and adaptive immunity (T effector lymphocytes and T regulatory lymphocytes - TREGs) may be involved in the development of hypertension, vascular injury and inflammation. However, no data are presently available in humans about possible relationships between T-lymphocyte subtypes and microvascular oxidative stress. Our objective was to investigate possible relationships between T-lymphocyte subtypes and systemic and microvascular oxidative stress in a population of normotensive subjects and hypertensive patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
