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IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishTools that extract phenotype alterations from transcriptomic data are important to improve the interpretation of biological studies. PATHChange is a statistical CRAN package designed to work with data downloaded from the Gene Expression Omnibus database (GEO) to determine differential pathway expression in comparative studies including control samples. In this paper we present details of the structure, implementation and an example of use of the package.
| Titolo: | The R implementation of the CRAN package PATHChange, a tool to study genetic pathway alterations in transcriptomic data |
| Autore/i: | Fontoura, Carla A. R. S; CASTELLANI, GASTONE; MOMBACH, JOSE CARLOS MERINO |
| Autore/i Unibo: | |
| Anno: | 2016 |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.compbiomed.2016.09.010 |
| Abstract: | Tools that extract phenotype alterations from transcriptomic data are important to improve the interpretation of biological studies. PATHChange is a statistical CRAN package designed to work with data downloaded from the Gene Expression Omnibus database (GEO) to determine differential pathway expression in comparative studies including control samples. In this paper we present details of the structure, implementation and an example of use of the package. |
| Data stato definitivo: | 2017-05-17T14:31:10Z |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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