The lack of early diagnosis, progression markers and effective pharmacological treatment has dramatic unfavourable effects on clinical outcomes in patients with peripheral artery disease (PAD). Addressing these issues will require dissecting the molecular mechanisms underlying this disease. We sought to characterize the Notch signaling and atherosclerosis relevant markers in lesions from femoral arteries of symptomatic PAD patients.

Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study

FORTINI, CINZIA;PANNELLA, MICAELA;CALICETI, CRISTIANA;CASTRIOTA, FAUSTO;FERRARI, ROBERTO;CREMONESI, ALBERTO
2017

Abstract

The lack of early diagnosis, progression markers and effective pharmacological treatment has dramatic unfavourable effects on clinical outcomes in patients with peripheral artery disease (PAD). Addressing these issues will require dissecting the molecular mechanisms underlying this disease. We sought to characterize the Notch signaling and atherosclerosis relevant markers in lesions from femoral arteries of symptomatic PAD patients.
Aquila, Giorgio; Fortini, Cinzia; Pannuti, Antonio; Delbue, Serena; Pannella, Micaela; Morelli, Marco Bruno; Caliceti, Cristiana; Castriota, Fausto; de Mattei, Monica; Ongaro, Alessia; Pellati, Agnese; Ferrante, Pasquale; Miele, Lucio; Tavazzi, Luigi; Ferrari, Roberto; Rizzo, Paola; Cremonesi, Alberto
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/585605
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