The aim of the present review is to discuss about the role of new probes for molecular imaging in the evaluation of prostate cancer (PCa). This review focuses particularly on the role of new promising radiotracers for the molecular imaging with PET/computed tomography in the detection of PCa recurrence. The role of these new imaging techniques to guide lesion-target therapies and the potential application of these molecular probes as theranostics agents is discussed. Finally, the molecular mechanisms underlying resistance to castration in PCa and the maintenance of active androgen receptor are discussed.
Molecular Imaging and Precision Medicine in Prostate Cancer / Francesco Ceci; Michelangelo Fiorentino; Paolo Castellucci; Stefano Fanti. - In: PET CLINICS. - ISSN 1556-8598. - ELETTRONICO. - 12 - Molecular Imaging and Precision Medicine, Part I:1(2017), pp. 83-92. [10.1016/j.cpet.2016.08.004]
Molecular Imaging and Precision Medicine in Prostate Cancer
Francesco Ceci;Michelangelo Fiorentino;Paolo Castellucci;Stefano Fanti
2017
Abstract
The aim of the present review is to discuss about the role of new probes for molecular imaging in the evaluation of prostate cancer (PCa). This review focuses particularly on the role of new promising radiotracers for the molecular imaging with PET/computed tomography in the detection of PCa recurrence. The role of these new imaging techniques to guide lesion-target therapies and the potential application of these molecular probes as theranostics agents is discussed. Finally, the molecular mechanisms underlying resistance to castration in PCa and the maintenance of active androgen receptor are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
