Peptide-15 (P-15) is an analogue of the cell binding domain of collagen. P-15 has been shown to facilitate physiological to process in a way similar to collagen, to serve as anchorage for cells, and to promote the binding, migration and differentiation of cells. However, how P-15 alters osteoblast activity to promote bone formation is poorly understood. To study the osteoinductive properties of peptide P-15, we analyzed the expression levels of bone related genes in human mesenchymal stem cells treated with this biomaterial.
Early effects of p-15 on human bone marrow stem cells / Sollazzo, Vincenzo; Palmieri, Annalisa; Girardi, Ambra; Farinella, Francesca; Carinci, Francesco. - In: EJOURNAL OF ORAL MAXILLOFACIAL RESEARCH. - ISSN 2029-283X. - ELETTRONICO. - 1:1(2010), pp. e4-e4. [10.5037/jomr.2010.1104]
Early effects of p-15 on human bone marrow stem cells
PALMIERI, ANNALISA;
2010
Abstract
Peptide-15 (P-15) is an analogue of the cell binding domain of collagen. P-15 has been shown to facilitate physiological to process in a way similar to collagen, to serve as anchorage for cells, and to promote the binding, migration and differentiation of cells. However, how P-15 alters osteoblast activity to promote bone formation is poorly understood. To study the osteoinductive properties of peptide P-15, we analyzed the expression levels of bone related genes in human mesenchymal stem cells treated with this biomaterial.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
