Cardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of “hypertrophy.” Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA.
Gagliardi, C., Tabacchi, E., Bonfiglioli, R., Diodato, S., Nanni, C., Guidalotti, P., et al. (2017). Does the etiology of cardiac amyloidosis determine the myocardial uptake of [18F]-NaF PET/CT?. JOURNAL OF NUCLEAR CARDIOLOGY, 24(2), 746-749 [10.1007/s12350-016-0457-8].
Does the etiology of cardiac amyloidosis determine the myocardial uptake of [18F]-NaF PET/CT?
GAGLIARDI, CHRISTIAN;TABACCHI, ELENA;BONFIGLIOLI, RACHELE;DIODATO, STEFANIA;NANNI, CRISTINA;LORENZINI, MASSIMILIANO;LODI, FILIPPO;MILANDRI, AGNESE;RAPEZZI, CLAUDIO;FANTI, STEFANO
2017
Abstract
Cardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of “hypertrophy.” Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
