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EnglishCardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of “hypertrophy.” Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA.
| Titolo: | Does the etiology of cardiac amyloidosis determine the myocardial uptake of [18F]-NaF PET/CT? |
| Autore/i: | GAGLIARDI, CHRISTIAN; TABACCHI, ELENA; BONFIGLIOLI, RACHELE; DIODATO, STEFANIA; NANNI, CRISTINA; Guidalotti, Pierluigi; LORENZINI, MASSIMILIANO; LODI, FILIPPO; MILANDRI, AGNESE; RAPEZZI, CLAUDIO; FANTI, STEFANO |
| Autore/i Unibo: | |
| Anno: | 2017 |
| Rivista: | |
| Digital Object Identifier (DOI): | 10.1007/s12350-016-0457-8 |
| Abstract: | Cardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of “hypertrophy.” Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA. |
| Data stato definitivo: | 2016-11-09T13:11:40Z |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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