In accordance with current guidelines, patients discharged after acute myocardial infarction (AMI) are usually prescribed agents acting on the renin-angiotensin system (ACE-I/ARB). However, adherence to prescribing medications is a recognized problem and most studies demonstrating the value of adherence were limited by their non-randomized design and by 'healthy-adherer' bias. Herein we sought to evaluate the relationship between adherence to ACE-I/ARB and risk of subsequent AMIs, by using the self-controlled case-series design which virtually eliminates interpersonal confounding, being based on intrapersonal comparisons.

Adherence to agents acting on the renin-angiotensin system in secondary prevention of non-fatal myocardial infarction: a self-controlled case-series study / Ortolani, Paolo; Di Bartolomeo, Stefano; Marino, Massimiliano; Vagnarelli, Fabio; Guastaroba, Paolo; Rapezzi, Claudio; De Palma, Rossana. - In: EUROPEAN HEART JOURNAL. CARDIOVASCULAR PHARMACOTHERAPY. - ISSN 2055-6845. - STAMPA. - 1:4(2015), pp. 254-259. [10.1093/ehjcvp/pvv028]

Adherence to agents acting on the renin-angiotensin system in secondary prevention of non-fatal myocardial infarction: a self-controlled case-series study

ORTOLANI, PAOLO;VAGNARELLI, FABIO;RAPEZZI, CLAUDIO;
2015

Abstract

In accordance with current guidelines, patients discharged after acute myocardial infarction (AMI) are usually prescribed agents acting on the renin-angiotensin system (ACE-I/ARB). However, adherence to prescribing medications is a recognized problem and most studies demonstrating the value of adherence were limited by their non-randomized design and by 'healthy-adherer' bias. Herein we sought to evaluate the relationship between adherence to ACE-I/ARB and risk of subsequent AMIs, by using the self-controlled case-series design which virtually eliminates interpersonal confounding, being based on intrapersonal comparisons.
2015
Adherence to agents acting on the renin-angiotensin system in secondary prevention of non-fatal myocardial infarction: a self-controlled case-series study / Ortolani, Paolo; Di Bartolomeo, Stefano; Marino, Massimiliano; Vagnarelli, Fabio; Guastaroba, Paolo; Rapezzi, Claudio; De Palma, Rossana. - In: EUROPEAN HEART JOURNAL. CARDIOVASCULAR PHARMACOTHERAPY. - ISSN 2055-6845. - STAMPA. - 1:4(2015), pp. 254-259. [10.1093/ehjcvp/pvv028]
Ortolani, Paolo; Di Bartolomeo, Stefano; Marino, Massimiliano; Vagnarelli, Fabio; Guastaroba, Paolo; Rapezzi, Claudio; De Palma, Rossana
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/566793
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