The asymmetric organocatalytic transfer hydrogenation of β-acylamino and β-tert-butyloxycarbonylamino nitroolefins has been successfully realised in excellent enantioselectivities and yields (up to >99% ee, 97% yield) with a simple thiourea catalyst and a Hantzsch ester as hydrogen source, giving a direct access to enantiomerically pure β-amino nitroalkanes. (Figure presented.).
Ferraro, A., Bernardi, L., Fochi, M. (2016). Organocatalytic Enantioselective Transfer Hydrogenation of β-Amino Nitroolefins. ADVANCED SYNTHESIS & CATALYSIS, 358(10), 1561-1565 [10.1002/adsc.201600061].
Organocatalytic Enantioselective Transfer Hydrogenation of β-Amino Nitroolefins
BERNARDI, LUCA;FOCHI, MARIAFRANCESCA
2016
Abstract
The asymmetric organocatalytic transfer hydrogenation of β-acylamino and β-tert-butyloxycarbonylamino nitroolefins has been successfully realised in excellent enantioselectivities and yields (up to >99% ee, 97% yield) with a simple thiourea catalyst and a Hantzsch ester as hydrogen source, giving a direct access to enantiomerically pure β-amino nitroalkanes. (Figure presented.).File in questo prodotto:
Eventuali allegati, non sono esposti
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
