The synthetic approach to methyl N-(tert-butoxycarbonyl)- S-(3-thienyl)-L-cysteinate (1) and methyl N-(tert-butoxycarbonyl)- S-[2-(3-thienyl)ethyl]-L-cysteinate (2) through tosylate intermediates is reported and discussed. These compounds, which combine the properties of the cysteine side-chain with those of the thiophene ring represent both potential bioactive molecules and interesting synthons for the development of new materials.
R. Cagnoli, M. Lanzi, A. Mucci, F. Parenti, L. Schenetti (2005). Synthesis of two novel cysteine functionalized thiophenes. SYNTHESIS, 2, 267-271 [10.1055/s-2004-834930].
Synthesis of two novel cysteine functionalized thiophenes
LANZI, MASSIMILIANO;
2005
Abstract
The synthetic approach to methyl N-(tert-butoxycarbonyl)- S-(3-thienyl)-L-cysteinate (1) and methyl N-(tert-butoxycarbonyl)- S-[2-(3-thienyl)ethyl]-L-cysteinate (2) through tosylate intermediates is reported and discussed. These compounds, which combine the properties of the cysteine side-chain with those of the thiophene ring represent both potential bioactive molecules and interesting synthons for the development of new materials.File in questo prodotto:
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