Delayed gadolinium enhancement magnetic resonance (DE-MR) imaging can be used for in vivo detection of left atrium (LA) fibrosis and scarring, whose identification is important for atrial fibrillation (AF) treatment. This study presents a new tool for 3D visualization of cardiac LA fibrosis based on DE-MR imaging and its qualitative validation by comparison with electro-anatomic mapping (EAM). Angio-MR (MRA) and DE-MR images were acquired and registered applying an affine transformation. Automatic LA segmentation was obtained from MRA images. Color-coded gray level intensities of DE-MR images were used as texture for the LA 3D surface model. The comparison in 4 patients between our 3D surface model and the 3D EAM confirmed the qualitative correspondence between the low-potential areas and the high-enhanced areas in DE-MR. Preliminary results on volumetric visualization of LA fibrosis based on DE-MR and MRA data processing have shown promising results and simple thresholding of our color-coded map could lead to a fast 3D quantification and localization of LA fibrosis.
Leonardi, R., Veronesi, F., Severi, S., Mantovan, R., Corsi, C. (2014). Volumetric Identification of Left Atrial Fibrosis from Delayed Enhancement Magnetic Resonance Imaging in Atrial Fibrillation: Preliminary Results.
Volumetric Identification of Left Atrial Fibrosis from Delayed Enhancement Magnetic Resonance Imaging in Atrial Fibrillation: Preliminary Results
VERONESI, FEDERICO;SEVERI, STEFANO;CORSI, CRISTIANA
2014
Abstract
Delayed gadolinium enhancement magnetic resonance (DE-MR) imaging can be used for in vivo detection of left atrium (LA) fibrosis and scarring, whose identification is important for atrial fibrillation (AF) treatment. This study presents a new tool for 3D visualization of cardiac LA fibrosis based on DE-MR imaging and its qualitative validation by comparison with electro-anatomic mapping (EAM). Angio-MR (MRA) and DE-MR images were acquired and registered applying an affine transformation. Automatic LA segmentation was obtained from MRA images. Color-coded gray level intensities of DE-MR images were used as texture for the LA 3D surface model. The comparison in 4 patients between our 3D surface model and the 3D EAM confirmed the qualitative correspondence between the low-potential areas and the high-enhanced areas in DE-MR. Preliminary results on volumetric visualization of LA fibrosis based on DE-MR and MRA data processing have shown promising results and simple thresholding of our color-coded map could lead to a fast 3D quantification and localization of LA fibrosis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.