Electrospinning technology enables production of polymeric nanofibers in form of non-woven mats. Recently electrospun mats made of hydrolysable polymers have found application in the new field of tissue engineering as porous bioresorbable scaffolds to support cell growth. A poly(lactide-co-glycolide) random copolymer (PLGA) with an equimolar lactide and glycolide content was electrospun to obtain nanofibers. The in vitro hydrolytic degradation of nanofibrous PLGA mats was investigated with the aim to provide data for the design of scaffolds with defined bio-resorption rates.
C. Gualandi, M. Scandola, M.L. Focarete, M. Kawalec, P. Dobrzynski (2007). FABBRICAZIONE DI SUPPORTI NANOFIBROSI BIO-ASSORBIBILI DA ELETTROFILATURA. PISA : Pacini Editore SpA.
FABBRICAZIONE DI SUPPORTI NANOFIBROSI BIO-ASSORBIBILI DA ELETTROFILATURA
GUALANDI, CHIARA;SCANDOLA, MARIASTELLA;FOCARETE, MARIA LETIZIA;
2007
Abstract
Electrospinning technology enables production of polymeric nanofibers in form of non-woven mats. Recently electrospun mats made of hydrolysable polymers have found application in the new field of tissue engineering as porous bioresorbable scaffolds to support cell growth. A poly(lactide-co-glycolide) random copolymer (PLGA) with an equimolar lactide and glycolide content was electrospun to obtain nanofibers. The in vitro hydrolytic degradation of nanofibrous PLGA mats was investigated with the aim to provide data for the design of scaffolds with defined bio-resorption rates.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
