Aim: To evaluate outcome of an accelerated radiotherapy (RT) regimen in elderly patients with an early stage non-melanoma skin cancer (NMSC). Methods: Total RT dose was 30 Gy in 5 Gy fractions in six consecutive days. Results: Thirty-one patients were enrolled. Fourteen were aged ≥80 years. Acute skin and observed late toxicity were exclusively of grade 1. Thirty patients showed a complete response (median follow-up 30 months). Two-year actuarial local control was 93.2%. The cosmetic result wasmostly judged as good or excellent. Conclusions: Short-course RT in elderly NMSC patients produces >90% local control of disease.
Ferro, M., Deodato, F., Macchia, G., Gentileschi, S., Cilla, S., Torre, G., et al. (2015). Short-course radiotherapy in elderly patients with early stage non-melanoma skin cancer: A phase II study. CANCER INVESTIGATION, 33(2), 34-38 [10.3109/07357907.2014.998835].
Short-course radiotherapy in elderly patients with early stage non-melanoma skin cancer: A phase II study
MORGANTI, ALESSIO GIUSEPPE
2015
Abstract
Aim: To evaluate outcome of an accelerated radiotherapy (RT) regimen in elderly patients with an early stage non-melanoma skin cancer (NMSC). Methods: Total RT dose was 30 Gy in 5 Gy fractions in six consecutive days. Results: Thirty-one patients were enrolled. Fourteen were aged ≥80 years. Acute skin and observed late toxicity were exclusively of grade 1. Thirty patients showed a complete response (median follow-up 30 months). Two-year actuarial local control was 93.2%. The cosmetic result wasmostly judged as good or excellent. Conclusions: Short-course RT in elderly NMSC patients produces >90% local control of disease.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
