In human medicine, squamomelanocytic tumour is a malignant cutaneous neoplasm composed of closely intermingled neoplastic squamous cells and melanocytes. A multinodular gingival tumour in a 16-year-old, mixed breed neutered female dog was examined microscopically. Two populations of neoplastic cells, melanocytic and squamous epithelial cells were intermingled. The melanocytic cells were melan-A positive and cytokeratin AE1-AE3 negative and the squamous component was cytokeratin AE1-AE3 positive and melan-A negative. Bovine papillomavirus was not identified by immunohistochemistry or polymerase chain reaction. A diagnosis of squamomelanocytic tumour was made.
Muscatello, L., Avallone, G., Benazzi, C., Sarli, G., Porcellato, I., Brachelente, C., et al. (2016). Oral Squamomelanocytic Tumour in a Dog: A Unique Biphasic Cancer. JOURNAL OF COMPARATIVE PATHOLOGY, 154(2-3), 211-214 [10.1016/j.jcpa.2015.12.004].
Oral Squamomelanocytic Tumour in a Dog: A Unique Biphasic Cancer
MUSCATELLO, LUISA VERA;AVALLONE, GIANCARLO;BENAZZI, CINZIA;SARLI, GIUSEPPE;BRUNETTI, BARBARA
2016
Abstract
In human medicine, squamomelanocytic tumour is a malignant cutaneous neoplasm composed of closely intermingled neoplastic squamous cells and melanocytes. A multinodular gingival tumour in a 16-year-old, mixed breed neutered female dog was examined microscopically. Two populations of neoplastic cells, melanocytic and squamous epithelial cells were intermingled. The melanocytic cells were melan-A positive and cytokeratin AE1-AE3 negative and the squamous component was cytokeratin AE1-AE3 positive and melan-A negative. Bovine papillomavirus was not identified by immunohistochemistry or polymerase chain reaction. A diagnosis of squamomelanocytic tumour was made.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
