In human medicine, squamomelanocytic tumour is a malignant cutaneous neoplasm composed of closely intermingled neoplastic squamous cells and melanocytes. A multinodular gingival tumour in a 16-year-old, mixed breed neutered female dog was examined microscopically. Two populations of neoplastic cells, melanocytic and squamous epithelial cells were intermingled. The melanocytic cells were melan-A positive and cytokeratin AE1-AE3 negative and the squamous component was cytokeratin AE1-AE3 positive and melan-A negative. Bovine papillomavirus was not identified by immunohistochemistry or polymerase chain reaction. A diagnosis of squamomelanocytic tumour was made.
Oral Squamomelanocytic Tumour in a Dog: A Unique Biphasic Cancer / Muscatello, L.V; Avallone, G.; Benazzi, C.; Sarli, G.; Porcellato, I.; Brachelente, C.; Brunetti, B.. - In: JOURNAL OF COMPARATIVE PATHOLOGY. - ISSN 0021-9975. - STAMPA. - 154:2-3(2016), pp. 211-214. [10.1016/j.jcpa.2015.12.004]
Oral Squamomelanocytic Tumour in a Dog: A Unique Biphasic Cancer
MUSCATELLO, LUISA VERA;AVALLONE, GIANCARLO;BENAZZI, CINZIA;SARLI, GIUSEPPE;BRUNETTI, BARBARA
2016
Abstract
In human medicine, squamomelanocytic tumour is a malignant cutaneous neoplasm composed of closely intermingled neoplastic squamous cells and melanocytes. A multinodular gingival tumour in a 16-year-old, mixed breed neutered female dog was examined microscopically. Two populations of neoplastic cells, melanocytic and squamous epithelial cells were intermingled. The melanocytic cells were melan-A positive and cytokeratin AE1-AE3 negative and the squamous component was cytokeratin AE1-AE3 positive and melan-A negative. Bovine papillomavirus was not identified by immunohistochemistry or polymerase chain reaction. A diagnosis of squamomelanocytic tumour was made.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
