The expression of taste receptors (TASRs) and their signalling molecules in the gastrointestinal (GI) epithelial cells, including enteroendocrine cells (EECs), suggests they participate in chemosensing mechanisms influencing GI physiology via the release of endocrine messengers. TASRs mediate gustatory signalling by interacting with different transducers, including α-gustducin (Gαgust) and α-transducin (Gαtran) G protein subunits. This study tested whether Gαtran and Gαgust immunoreactive (-IR) cells are affected by a short-term (3 days) and long-term (30 days) high protein (Hp) diet in the pig GI tract.
Regulation of α-Transducin and α-Gustducin Expression by a High Protein Diet in the Pig Gastrointestinal Tract / DE GIORGIO, Roberto; Mazzoni, Maurizio; Vallorani, Claudia; Latorre, Rocco; Bombardi, Cristiano; Bacci, MARIA LAURA; Forni, Monica; Falconi, Mirella; Catia, Sternini; Clavenzani, Paolo. - In: PLOS ONE. - ISSN 1932-6203. - ELETTRONICO. - 11:2(2016), pp. e0148954.1-e0148954.17. [10.1371/journal.pone.0148954]
Regulation of α-Transducin and α-Gustducin Expression by a High Protein Diet in the Pig Gastrointestinal Tract
DE GIORGIO, ROBERTO;MAZZONI, MAURIZIO;VALLORANI, CLAUDIA;LATORRE, ROCCO;BOMBARDI, CRISTIANO;BACCI, MARIA LAURA;FORNI, MONICA;FALCONI, MIRELLA;CLAVENZANI, PAOLO
2016
Abstract
The expression of taste receptors (TASRs) and their signalling molecules in the gastrointestinal (GI) epithelial cells, including enteroendocrine cells (EECs), suggests they participate in chemosensing mechanisms influencing GI physiology via the release of endocrine messengers. TASRs mediate gustatory signalling by interacting with different transducers, including α-gustducin (Gαgust) and α-transducin (Gαtran) G protein subunits. This study tested whether Gαtran and Gαgust immunoreactive (-IR) cells are affected by a short-term (3 days) and long-term (30 days) high protein (Hp) diet in the pig GI tract.| File | Dimensione | Formato | |
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92) Regulation of α-Transducin and α-Gustducin expression by a high protein diet in pig GI tract 2016.pdf
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