We evaluated the analytical performance of a liquid chromatography-tandem mass spectrometry assay to detect carbapenemase activity in a group of carbapenemase-producing Enterobacteriaceae by meropenem hydrolysis. This one-hour method showed a sensitivity of 94% and a specificity of 100%, representing a rapid and reliable option compared to conventional phenotypic assays

Use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) to detect carbapenemase production in Enterobacteriaceae by a rapid meropenem degradation assay / Foschi, C; Franza, V; Conti, M; Tamburini, Mv; Roncarati, G; Cordovana, M; Smirnova, V; Patrono, D; Mancini, R; Landini, Mp; Ambretti, S. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - STAMPA. - 38:4(2015), pp. 571-576.

Use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) to detect carbapenemase production in Enterobacteriaceae by a rapid meropenem degradation assay

FOSCHI, CLAUDIO;LANDINI, MARIA PAOLA;Ambretti, S.
2015

Abstract

We evaluated the analytical performance of a liquid chromatography-tandem mass spectrometry assay to detect carbapenemase activity in a group of carbapenemase-producing Enterobacteriaceae by meropenem hydrolysis. This one-hour method showed a sensitivity of 94% and a specificity of 100%, representing a rapid and reliable option compared to conventional phenotypic assays
2015
Use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) to detect carbapenemase production in Enterobacteriaceae by a rapid meropenem degradation assay / Foschi, C; Franza, V; Conti, M; Tamburini, Mv; Roncarati, G; Cordovana, M; Smirnova, V; Patrono, D; Mancini, R; Landini, Mp; Ambretti, S. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - STAMPA. - 38:4(2015), pp. 571-576.
Foschi, C; Franza, V; Conti, M; Tamburini, Mv; Roncarati, G; Cordovana, M; Smirnova, V; Patrono, D; Mancini, R; Landini, Mp; Ambretti, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/531142
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