Nonsteroidal anti-inflammatory drugs (NSAIDs) are the class of drugs most commonly used in equine medicine. This article reviews the literature on the different NSAIDs used in equine neonatology: flunixin meglumine, phenylbutazone, ibuprofen, ketoprofen, meloxicam, and firocoxib. These drugs are routinely used in equine adults, but in neonatal foals, the risk of side effects should be carefully evaluated. Many of the studies on NSAID pharmacokinetics in neonatal foals have been performed on healthy animals, and more information is needed to determine the appropriate dosage in the compromised equine neonate. The review highlights the lack of specific NSAID dosages for compromised foals and emphasizes the risk of side effects in the neonate.
Castagnetti, C., Mariella, J. (2015). Anti-inflammatory Drugs in Equine Neonatal Medicine. Part I: Nonsteroidal Anti-inflammatory Drugs. JOURNAL OF EQUINE VETERINARY SCIENCE, 35, 475-480 [10.1016/j.jevs.2015.02.008].
Anti-inflammatory Drugs in Equine Neonatal Medicine. Part I: Nonsteroidal Anti-inflammatory Drugs
CASTAGNETTI, CAROLINA;MARIELLA, JOLE
2015
Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the class of drugs most commonly used in equine medicine. This article reviews the literature on the different NSAIDs used in equine neonatology: flunixin meglumine, phenylbutazone, ibuprofen, ketoprofen, meloxicam, and firocoxib. These drugs are routinely used in equine adults, but in neonatal foals, the risk of side effects should be carefully evaluated. Many of the studies on NSAID pharmacokinetics in neonatal foals have been performed on healthy animals, and more information is needed to determine the appropriate dosage in the compromised equine neonate. The review highlights the lack of specific NSAID dosages for compromised foals and emphasizes the risk of side effects in the neonate.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
