While a systematic approach to weaning reduces the rate of extubation failure in intubated brain-injured patients, no data are available on the weaning outcome of these patients after tracheotomy. We aimed to assess whether a systematic approach to disconnect tracheotomized neurological and neurosurgical patients off the ventilator (intervention) is superior to the sole physician's judgment (control). Based on previous work in intubated patients, we hypothesized a reduction of the rate of failure within 48 h from 15 to 5 %. Secondary endpoints were duration of mechanical ventilation, ICU length of stay and mortality.
Evaluation of a systematic approach to weaning of tracheotomized neurological patients: an early interrupted randomized controlled trial / Vaschetto, Rosanna; Frigerio, Pamela; Sommariva, Maurizio; Boggero, Arianna; Rondi, Valentina; Grossi, Francesca; Cavuto, Silvio; Nava, Stefano; Corte, Francesco Della; Navalesi, Paolo. - In: ANNALS OF INTENSIVE CARE. - ISSN 2110-5820. - STAMPA. - 5:1(2015), pp. 54-59. [10.1186/s13613-015-0098-0]
Evaluation of a systematic approach to weaning of tracheotomized neurological patients: an early interrupted randomized controlled trial
NAVA, STEFANO;
2015
Abstract
While a systematic approach to weaning reduces the rate of extubation failure in intubated brain-injured patients, no data are available on the weaning outcome of these patients after tracheotomy. We aimed to assess whether a systematic approach to disconnect tracheotomized neurological and neurosurgical patients off the ventilator (intervention) is superior to the sole physician's judgment (control). Based on previous work in intubated patients, we hypothesized a reduction of the rate of failure within 48 h from 15 to 5 %. Secondary endpoints were duration of mechanical ventilation, ICU length of stay and mortality.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
