In order to well distinguish different tissues of the human body, it is of paramount importance to find procedures and sequences that improve the contrast of Magnetic Resonance Imaging (MRI) images. In particular, the possibility to image only specific parts of organs and/or tissues while ignoring all the others is a very valuable feature. A way to address this problem is to develop dedicated MRI sequences able to filter the 1H nuclei signals on the basis of the different longitudinal relaxation times (T1) of the tissues and to produce images where components are suppressed. Instead of using standard signal selection/attenuation sequences, such as the Short Time Inversion Recovery and Multiple Inversion Recovery, whose effects are to zero the signal for a discrete number of T1 values, we developed the Parametrically Enabled Relaxation Filters with Double and multiple Inversion (PERFIDI) filter sequences. These sequences acting on a range of T1 behave as electronic band-pass, high-pass and low-pass filters, primarily focused on the components which pass through, rather than on those blocked. We tested PERFIDI filter sequences on a synthetic two-component test tube sample. Preliminary applications on biological tissues have shown that this technique can effectively work on a range of T1 values.

Perfidi Filter sequences to acquire MRI images with specific range of T1 signal components suppressed

BORTOLOTTI, VILLIAM;BRIZI, LEONARDO;FANTAZZINI, PAOLA;MARIANI, MANUEL;VANNINI, MARIANNA;VASINI, ESTER MARIA
2014

Abstract

In order to well distinguish different tissues of the human body, it is of paramount importance to find procedures and sequences that improve the contrast of Magnetic Resonance Imaging (MRI) images. In particular, the possibility to image only specific parts of organs and/or tissues while ignoring all the others is a very valuable feature. A way to address this problem is to develop dedicated MRI sequences able to filter the 1H nuclei signals on the basis of the different longitudinal relaxation times (T1) of the tissues and to produce images where components are suppressed. Instead of using standard signal selection/attenuation sequences, such as the Short Time Inversion Recovery and Multiple Inversion Recovery, whose effects are to zero the signal for a discrete number of T1 values, we developed the Parametrically Enabled Relaxation Filters with Double and multiple Inversion (PERFIDI) filter sequences. These sequences acting on a range of T1 behave as electronic band-pass, high-pass and low-pass filters, primarily focused on the components which pass through, rather than on those blocked. We tested PERFIDI filter sequences on a synthetic two-component test tube sample. Preliminary applications on biological tissues have shown that this technique can effectively work on a range of T1 values.
Proceedings XIX International Conference on Mechanics in Medicine and Biology
443
447
Bortolotti, V.; Brizi, L.; Fantazzini, P.; Mariani, M.; Vannini, M.; Vasini, E.M
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/523879
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