We report on a 46-year-old athletic patient, previously treated with anterior cruciate ligament reconstruction, with large degenerative chondral lesions of the medial femoral condyle, trochlea and patella, which was successfully treated with a closing-wedge high tibial osteotomy and the implant of a newly developed biomimetic nanostructured osteochondral bioactive scaffold. After 1 year of follow-up the patient was pain-free, had full knee range of motion, and had returned to his pre-operation level of athletic activity. MRI evaluation at 6 months showed that the implant gave a hyaline-like signal as well as a good restoration of the articular surface, with minimal subchondral bone oedema. Subchondral oedema was almost non-visible at 12 months
Novel nano-composite multi-layered biomaterial for the treatment of multifocal degenerative cartilage lesions / E. Kon; M. Delcogliano; G. Filardo; G. Altadonna; M. Marcacci. - In: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. - ISSN 0942-2056. - STAMPA. - 17:11(2009), pp. 1312-1315. [10.1007/s00167-009-0819-8]
Novel nano-composite multi-layered biomaterial for the treatment of multifocal degenerative cartilage lesions
KON, ELIZAVETA;DELCOGLIANO, MARCO;FILARDO, GIUSEPPE;MARCACCI, MAURILIO
2009
Abstract
We report on a 46-year-old athletic patient, previously treated with anterior cruciate ligament reconstruction, with large degenerative chondral lesions of the medial femoral condyle, trochlea and patella, which was successfully treated with a closing-wedge high tibial osteotomy and the implant of a newly developed biomimetic nanostructured osteochondral bioactive scaffold. After 1 year of follow-up the patient was pain-free, had full knee range of motion, and had returned to his pre-operation level of athletic activity. MRI evaluation at 6 months showed that the implant gave a hyaline-like signal as well as a good restoration of the articular surface, with minimal subchondral bone oedema. Subchondral oedema was almost non-visible at 12 monthsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.