Quetiapine (QTP) has been shown to be effective as an acute treatment in patients with bipolar depression. Nonetheless, the time at onset of QTP antidepressant action has not been clarified. We aimed to evaluate the onset of the antidepressant effect of QTP extended release (XR) in bipolar depression. We also compared the different efficacy and adverse effect profile of 300- and 600-mg/d dosages.
Porcelli, S., Balzarro, B., De Ronchi, D., Serretti, A. (2014). Quetiapine extended release: Preliminary evidence of a rapid onset of the antidepressant effect in bipolar depression. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 34(3), 303-306 [10.1097/JCP.0000000000000103].
Quetiapine extended release: Preliminary evidence of a rapid onset of the antidepressant effect in bipolar depression
PORCELLI, STEFANO LUIGI;DE RONCHI, DIANA;SERRETTI, ALESSANDRO
2014
Abstract
Quetiapine (QTP) has been shown to be effective as an acute treatment in patients with bipolar depression. Nonetheless, the time at onset of QTP antidepressant action has not been clarified. We aimed to evaluate the onset of the antidepressant effect of QTP extended release (XR) in bipolar depression. We also compared the different efficacy and adverse effect profile of 300- and 600-mg/d dosages.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.