The search for a minimally invasive solution to improve the status of a pathologic joint surface and allow a fast return to full activity is highly desirable. In this landscape, a novel promising injective treatment is platelet-rich plasma (PRP), a blood derivative characterized by a higher platelet concentration than that of whole blood. When activated, platelets release a group of bioactive molecules that ultimately promote cellular recruitment, growth, and morphogenesis, and modulate inflammation as well [7]. Therefore, PRP is an appealing biological approach to favour the healing of tissues, such as cartilage, otherwise doomed by a low healing potential
PRP: Product Rich in Placebo? / Giuseppe Filardo; Elizaveta Kon. - In: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. - ISSN 0942-2056. - ELETTRONICO. - 24:12(2016), pp. 3702-3703. [10.1007/s00167-015-3778-2]
PRP: Product Rich in Placebo?
FILARDO, GIUSEPPE;KON, ELIZAVETA
2016
Abstract
The search for a minimally invasive solution to improve the status of a pathologic joint surface and allow a fast return to full activity is highly desirable. In this landscape, a novel promising injective treatment is platelet-rich plasma (PRP), a blood derivative characterized by a higher platelet concentration than that of whole blood. When activated, platelets release a group of bioactive molecules that ultimately promote cellular recruitment, growth, and morphogenesis, and modulate inflammation as well [7]. Therefore, PRP is an appealing biological approach to favour the healing of tissues, such as cartilage, otherwise doomed by a low healing potentialI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
