The frequent occurrence of chiral 1-substituted-1,2,3,4-tetrahydroisoquinoline ring systems in a large number of alkaloids, possessing a broad spectrum of biological and pharmaceutical properties, has prompted out a considerable interest in their synthesis. Economical and valuable stereoselective processes based on organocatalytic transformations represent a new avenue for approaching isoquinoline alkaloids with efficiency and creativity.

Stereoselective Organocatalytic Addition of Nucleophiles to Isoquinolinium and 3,4-dihydroisoquinolinium Ions: A Simple Approach for the Synthesis of Isoquinoline Alkaloids / Gualandi, Andrea; Mengozzi, Luca; Manoni, Elisabetta; Cozzi, Pier Giorgio. - In: CATALYSIS LETTERS. - ISSN 1011-372X. - ELETTRONICO. - 145:1(2015), pp. 398-419. [10.1007/s10562-014-1396-0]

Stereoselective Organocatalytic Addition of Nucleophiles to Isoquinolinium and 3,4-dihydroisoquinolinium Ions: A Simple Approach for the Synthesis of Isoquinoline Alkaloids

GUALANDI, ANDREA;MENGOZZI, LUCA;MANONI, ELISABETTA;COZZI, PIER GIORGIO
2015

Abstract

The frequent occurrence of chiral 1-substituted-1,2,3,4-tetrahydroisoquinoline ring systems in a large number of alkaloids, possessing a broad spectrum of biological and pharmaceutical properties, has prompted out a considerable interest in their synthesis. Economical and valuable stereoselective processes based on organocatalytic transformations represent a new avenue for approaching isoquinoline alkaloids with efficiency and creativity.
2015
Stereoselective Organocatalytic Addition of Nucleophiles to Isoquinolinium and 3,4-dihydroisoquinolinium Ions: A Simple Approach for the Synthesis of Isoquinoline Alkaloids / Gualandi, Andrea; Mengozzi, Luca; Manoni, Elisabetta; Cozzi, Pier Giorgio. - In: CATALYSIS LETTERS. - ISSN 1011-372X. - ELETTRONICO. - 145:1(2015), pp. 398-419. [10.1007/s10562-014-1396-0]
Gualandi, Andrea; Mengozzi, Luca; Manoni, Elisabetta; Cozzi, Pier Giorgio
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/519290
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 24
  • ???jsp.display-item.citation.isi??? 23
social impact