Detection of target substances at very low concentration by using molecular stochastic sensing might open new directions for diagnostic tools. This paper presents a compact and low-cost electronic system to record events derived from ligand-gated ion channels embedded in an array of artificial lipid bilayer substrates. In our approach, a Surface Mount Technology electronic system has been designed to be interfaced with a 4ÿ3 array of spots. The currents through each spot of one row are concurrently readout and digitized by three current-mode ¿¿ (Delta Sigma) analog to digital converters. The output data streams are sent to a digital acquisition card for being recorded and post-processed by a PC.
A Delta-Sigma Approach for Ion Channel Based Biosensor Arrays / M. Bennati; F. Lodesani; M. Crescentini; A. Mariani; M. Tartagni. - STAMPA. - (2007), pp. 835-838. (Intervento presentato al convegno TRANSDUCERS 2007 Solid-State Sensors, Actuators and Microsystems Conference tenutosi a Lyon (FR) nel 2007).
A Delta-Sigma Approach for Ion Channel Based Biosensor Arrays
BENNATI, MARCO;LODESANI, FRANCESCO;TARTAGNI, MARCO
2007
Abstract
Detection of target substances at very low concentration by using molecular stochastic sensing might open new directions for diagnostic tools. This paper presents a compact and low-cost electronic system to record events derived from ligand-gated ion channels embedded in an array of artificial lipid bilayer substrates. In our approach, a Surface Mount Technology electronic system has been designed to be interfaced with a 4ÿ3 array of spots. The currents through each spot of one row are concurrently readout and digitized by three current-mode ¿¿ (Delta Sigma) analog to digital converters. The output data streams are sent to a digital acquisition card for being recorded and post-processed by a PC.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
