Detection of target substances at very low concentration by using molecular stochastic sensing might open new directions for diagnostic tools. This paper presents a compact and low-cost electronic system to record events derived from ligand-gated ion channels embedded in an array of artificial lipid bilayer substrates. In our approach, a Surface Mount Technology electronic system has been designed to be interfaced with a 4ÿ3 array of spots. The currents through each spot of one row are concurrently readout and digitized by three current-mode ¿¿ (Delta Sigma) analog to digital converters. The output data streams are sent to a digital acquisition card for being recorded and post-processed by a PC.

A Delta-Sigma Approach for Ion Channel Based Biosensor Arrays

BENNATI, MARCO;LODESANI, FRANCESCO;TARTAGNI, MARCO
2007

Abstract

Detection of target substances at very low concentration by using molecular stochastic sensing might open new directions for diagnostic tools. This paper presents a compact and low-cost electronic system to record events derived from ligand-gated ion channels embedded in an array of artificial lipid bilayer substrates. In our approach, a Surface Mount Technology electronic system has been designed to be interfaced with a 4ÿ3 array of spots. The currents through each spot of one row are concurrently readout and digitized by three current-mode ¿¿ (Delta Sigma) analog to digital converters. The output data streams are sent to a digital acquisition card for being recorded and post-processed by a PC.
Proceedings of TRANSDUCERS 2007 Solid-State Sensors, Actuators and Microsystems Conference
835
838
M. Bennati; F. Lodesani; M. Crescentini; A. Mariani; M. Tartagni
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/51879
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