After the assessment of the detector detection properties carried out in previous beamtimes at SYRMEP, our current aim is to test the prototypes of organic bendable X-ray 2x2 matrix detector operating with the experimental conditions typical of medical tests with the patients. In particular, the devices would be tested to assess the reliability of our system for two different analyses in medical diagnostic applications: 1.Planar Imaging typically employed for mammography. 2.Differential measurement to provide a density analysis of a sample composed of different materials. Figure 1a and b show the preliminary results obtained during a previous beamtime at SYRMEP with a 2x2 pixelated matrix detector. Thanks to the possibility to focus the beam in a very precise region of the active layer and to control the area of irradiation by means of precision slits and a CCD camera, we could control the position of irradiation within the matrix. The signal was simultaneously collected from the 4 devices through the 4 channel picoammeter and oscilloscope AH501, capable to detect the current variations (ΔI=Ion-Ioff) from each device and to real-time monitor the signal. In Figure 1a only pixels 1 and 4 were irradiated (beam energy of 17keV; device biased at 0.2V), as the CCD image shows (top); in the bottom the signals collected from the four pixels of the matrix are reported. Similarly, Figure 1b refers to the selective irradiation of pixels 2 and 3. Such a result represents the first demonstration of the reliability of our device as an imager. Therefore, the next experimental step to verify the actual device functionality would be the above mentioned “patient-operation mode” test, i. e. the operative test of the organic detector with the same experimental conditions of those employed in SYRMEP beamline during the diagnostic analyses with the patients. In addition, the possibility to use a synchrotron monochromatic X-ray beam will allow us to verify the possibility to exploit our system also for spectral imaging analyses, e.g. X-ray Color Computed Tomography (CT) scan, or as a density analyzer for different tissues of the human body, e. g. bones. It is worth noting that the conformability to any surface of the human body of our system (the flexibility of the structure is shown in Figure 1c), its low cost and its very low operative voltage (below 1V) make the here proposed sensor very suitable for medical diagnostic application. The above described measurements are thus crucial to reach a complete and reliable test of our prototype.

Esperimento 20150508 presso Sincrotrone ELETTRA Trieste, 10 shifts sulla beamline SYRMEP sul tema “Investigation of photon-to-charge carrier conversion processes in organic single crystals exposed to ionizing radiation ”,

FRABONI, BEATRICE
2015

Abstract

After the assessment of the detector detection properties carried out in previous beamtimes at SYRMEP, our current aim is to test the prototypes of organic bendable X-ray 2x2 matrix detector operating with the experimental conditions typical of medical tests with the patients. In particular, the devices would be tested to assess the reliability of our system for two different analyses in medical diagnostic applications: 1.Planar Imaging typically employed for mammography. 2.Differential measurement to provide a density analysis of a sample composed of different materials. Figure 1a and b show the preliminary results obtained during a previous beamtime at SYRMEP with a 2x2 pixelated matrix detector. Thanks to the possibility to focus the beam in a very precise region of the active layer and to control the area of irradiation by means of precision slits and a CCD camera, we could control the position of irradiation within the matrix. The signal was simultaneously collected from the 4 devices through the 4 channel picoammeter and oscilloscope AH501, capable to detect the current variations (ΔI=Ion-Ioff) from each device and to real-time monitor the signal. In Figure 1a only pixels 1 and 4 were irradiated (beam energy of 17keV; device biased at 0.2V), as the CCD image shows (top); in the bottom the signals collected from the four pixels of the matrix are reported. Similarly, Figure 1b refers to the selective irradiation of pixels 2 and 3. Such a result represents the first demonstration of the reliability of our device as an imager. Therefore, the next experimental step to verify the actual device functionality would be the above mentioned “patient-operation mode” test, i. e. the operative test of the organic detector with the same experimental conditions of those employed in SYRMEP beamline during the diagnostic analyses with the patients. In addition, the possibility to use a synchrotron monochromatic X-ray beam will allow us to verify the possibility to exploit our system also for spectral imaging analyses, e.g. X-ray Color Computed Tomography (CT) scan, or as a density analyzer for different tissues of the human body, e. g. bones. It is worth noting that the conformability to any surface of the human body of our system (the flexibility of the structure is shown in Figure 1c), its low cost and its very low operative voltage (below 1V) make the here proposed sensor very suitable for medical diagnostic application. The above described measurements are thus crucial to reach a complete and reliable test of our prototype.
2015
2015
Beatrice Fraboni
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/518148
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