Ewing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the Mesenchymal Stem Cell (MSC) is currently accepted as the most probable cell of origin.
Amaral, A., Manara, M., Berghuis, D., Ordonez, J., Biscuola, M., Lopez-Garcia, M., et al. (2014). Characterization of human mesenchymal stem cells from Ewing sarcoma patients. Pathogenetic implications. PLOS ONE, 9(2), 1-9 [10.1371/journal.pone.0085814].
Characterization of human mesenchymal stem cells from Ewing sarcoma patients. Pathogenetic implications
ALVIANO, FRANCESCO;SCOTLANDI, KATIA;
2014
Abstract
Ewing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the Mesenchymal Stem Cell (MSC) is currently accepted as the most probable cell of origin.File in questo prodotto:
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MSC Ewing Sarcoma Plos One_2014.pdf
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pone.0085814.s001.tif
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Descrizione: Figure S1: MFI of markers CD90, CD105, CD34 and CD45 in MSC-HD, MSC-P and EWS cell lines.
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pone.0085814.s002.doc
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Descrizione: ables S1 and S2. Table S1. Mab antibodies used in the multiparametric analysis and functional assays. Table S2. Percentage of Cells evaluated for each cell surface marker.
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