Ewing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the Mesenchymal Stem Cell (MSC) is currently accepted as the most probable cell of origin.

Characterization of human mesenchymal stem cells from Ewing sarcoma patients. Pathogenetic implications

ALVIANO, FRANCESCO;SCOTLANDI, KATIA;
2014

Abstract

Ewing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the Mesenchymal Stem Cell (MSC) is currently accepted as the most probable cell of origin.
Amaral, A.T.A.; Manara, M.C.; Berghuis, D.; Ordonez, J.L.; Biscuola, M.; Lopez-Garcia, M.A.; Osuna, D.; Lucarelli, E.; Alviano, F.; Lankester, A.; Scotlandi, K.; De Alava, E.
File in questo prodotto:
File Dimensione Formato  
MSC Ewing Sarcoma Plos One_2014.pdf

accesso aperto

Tipo: Versione (PDF) editoriale
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione 894.1 kB
Formato Adobe PDF
894.1 kB Adobe PDF Visualizza/Apri
pone.0085814.s001.tif

accesso aperto

Descrizione: Figure S1: MFI of markers CD90, CD105, CD34 and CD45 in MSC-HD, MSC-P and EWS cell lines.
Tipo: File Supplementare
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione 131.02 kB
Formato TIFF
131.02 kB TIFF Visualizza/Apri
pone.0085814.s002.doc

accesso aperto

Descrizione: ables S1 and S2. Table S1. Mab antibodies used in the multiparametric analysis and functional assays. Table S2. Percentage of Cells evaluated for each cell surface marker.
Tipo: File Supplementare
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione 108 kB
Formato Microsoft Word
108 kB Microsoft Word Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/517118
Citazioni
  • ???jsp.display-item.citation.pmc??? 20
  • Scopus 27
  • ???jsp.display-item.citation.isi??? 9
social impact