Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.
DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing
MORANDI, LUCA;GISSI, DAVIDE BARTOLOMEO;TARSITANO, ACHILLE;ASIOLI, SOFIA;DEL CORSO, GIACOMO;MARCHETTI, CLAUDIO;MONTEBUGNOLI, LUCIO;FOSCHINI, MARIA PIA
2015
Abstract
Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.File in questo prodotto:
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