Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.
Morandi, L., Gissi, D., Tarsitano, A., Asioli, S., Monti, V., Del Corso, G., et al. (2015). DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 1, 1-1 [10.1016/j.jcms.2015.07.028].
DNA methylation analysis by bisulfite next-generation sequencing for early detection of oral squamous cell carcinoma and high-grade squamous intraepithelial lesion from oral brushing
MORANDI, LUCA;GISSI, DAVIDE BARTOLOMEO;TARSITANO, ACHILLE;ASIOLI, SOFIA;DEL CORSO, GIACOMO;MARCHETTI, CLAUDIO;MONTEBUGNOLI, LUCIO;FOSCHINI, MARIA PIA
2015
Abstract
Oral squamous cell carcinoma (OSCC) is commonly preceded by oral potentially malignant lesions (OPML). The aim of the present study was to assess, by bisulfite next-generation sequencing (NGS), the methylation status of a list of candidate genes obtained from oral brushings to early detect OPML and OSCC.| File | Dimensione | Formato | |
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