Bioresorbable new terpolymers of L-lactide, glycolide and trimethylene carbonate with different composition were synthesized via ring opening polymerization reaction of the cyclic monomers using low-toxicity zirconium (IV) acetylacetonate as initiator. The thermal and mechanical properties were investigated by means of thermogravimetry, differential scanning calorimetry, stress-strain measurements and dynamical mechanical analysis. The glass transition temperature of the terpolymers changes with composition from 12°C to 42°C in a predictable manner. All terpolymers display shape memory properties and, after undergoing 100% deformation, they recover the permanent shape in a time frame of seconds. Terpolymers with high L-lactide content show a glass transition in the range 38-42°C, recovery temperature close to body temperature and good recovery ratio (> 0.89). Low toxicity bioresorbable terpolymers with shape memory properties are promising new materials for biomedical applications

E. Zini, M. Scandola, P. Dobrzynski, J. Kasperczyk, M. Bero (2007). Novel (L-lactide-glycolide-trimethylene carbonate) terpolymers with shape memory properties. BIOMACROMOLECULES, 8, 3661-3667 [10.1021/bm700773s].

Novel (L-lactide-glycolide-trimethylene carbonate) terpolymers with shape memory properties

ZINI, ELISA;SCANDOLA, MARIASTELLA;
2007

Abstract

Bioresorbable new terpolymers of L-lactide, glycolide and trimethylene carbonate with different composition were synthesized via ring opening polymerization reaction of the cyclic monomers using low-toxicity zirconium (IV) acetylacetonate as initiator. The thermal and mechanical properties were investigated by means of thermogravimetry, differential scanning calorimetry, stress-strain measurements and dynamical mechanical analysis. The glass transition temperature of the terpolymers changes with composition from 12°C to 42°C in a predictable manner. All terpolymers display shape memory properties and, after undergoing 100% deformation, they recover the permanent shape in a time frame of seconds. Terpolymers with high L-lactide content show a glass transition in the range 38-42°C, recovery temperature close to body temperature and good recovery ratio (> 0.89). Low toxicity bioresorbable terpolymers with shape memory properties are promising new materials for biomedical applications
2007
E. Zini, M. Scandola, P. Dobrzynski, J. Kasperczyk, M. Bero (2007). Novel (L-lactide-glycolide-trimethylene carbonate) terpolymers with shape memory properties. BIOMACROMOLECULES, 8, 3661-3667 [10.1021/bm700773s].
E. Zini; M. Scandola; P. Dobrzynski; J. Kasperczyk; M. Bero
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/50491
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 96
  • ???jsp.display-item.citation.isi??? 89
social impact