This study aimed at identifying factors related to sentinel lymph node (SLN) involvement in patients with tubular, cribriform, mucinous or papillary breast carcinoma and those related to non-SLN metastases if an SLN was positive. Multivariate analyses involved logistic and stepwise regressions. The SLNs harboured metastases in 85 of 572 cases, 78 of whom underwent axillary dissection; 19 presented non-SLN positive disease. Lack of lymphovascular invasion, a tumour size < or = 10 mm and a single SLN removed were the factors predicting an SLN metastasis rate &lt;10%, and patients with these features could be candidates for no surgical axillary staging. A positive SLN proportion of < or = 50% and no lymphovascular invasion were associated with a &lt;10% rate of non-SLN invasion; patients with a positive SLN and these features could be candidates for the omission of completion axillary dissection. The opposite presentation of these factors would mandate SLN biopsy and axillary dissection, respectively.

Cserni G, Bianchi S, Vezzosi V, Arisio L, Bori R, Peterse JL, et al. (2007). Sentinel lymph node biopsy and non-sentinel node involvement in special type breast carcinomas with a good prognosis. EUROPEAN JOURNAL OF CANCER, 43, 1407-1414 [10.1016/j.ejca.2007.04.004].

Sentinel lymph node biopsy and non-sentinel node involvement in special type breast carcinomas with a good prognosis.

EUSEBI, VINCENZO;FOSCHINI, MARIA PIA;
2007

Abstract

This study aimed at identifying factors related to sentinel lymph node (SLN) involvement in patients with tubular, cribriform, mucinous or papillary breast carcinoma and those related to non-SLN metastases if an SLN was positive. Multivariate analyses involved logistic and stepwise regressions. The SLNs harboured metastases in 85 of 572 cases, 78 of whom underwent axillary dissection; 19 presented non-SLN positive disease. Lack of lymphovascular invasion, a tumour size < or = 10 mm and a single SLN removed were the factors predicting an SLN metastasis rate <10%, and patients with these features could be candidates for no surgical axillary staging. A positive SLN proportion of < or = 50% and no lymphovascular invasion were associated with a <10% rate of non-SLN invasion; patients with a positive SLN and these features could be candidates for the omission of completion axillary dissection. The opposite presentation of these factors would mandate SLN biopsy and axillary dissection, respectively.
2007
Cserni G, Bianchi S, Vezzosi V, Arisio L, Bori R, Peterse JL, et al. (2007). Sentinel lymph node biopsy and non-sentinel node involvement in special type breast carcinomas with a good prognosis. EUROPEAN JOURNAL OF CANCER, 43, 1407-1414 [10.1016/j.ejca.2007.04.004].
Cserni G; Bianchi S; Vezzosi V; Arisio L; Bori R; Peterse JL; Sapino A; Castellano I; Drijkoningen M; Kulka J; Eusebi V; Foschini MP; Bellocq JP; Mari...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/48979
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