Silver-doped organic–inorganic hybrid coatings were prepared starting from tetraethoxysilane and α-triethoxysilane terminated poly(ethylene)–block–poly(ethyleneglycole) using the sol–gel process. They were applied as a thin layer (600-1000 nm) to PE and PVC films and the antibacterial activity of the coated films was tested against Gram-negative (Escherichia coli ATCC 25922) and Gram-positive (Staphylococcus aureus ATCC 6538) bacteria. The effect of several parameters (such as organic-inorganic ratio, type of catalyst, time of post-curing, Silver-ion concentration, etc.) was investigated. Measurements at different contact times showed a rapid decrease of the viable count for both the tested strains. The highest antibacterial activity (more than 6 log reduction within 6 hours starting from 106 CFU ml-1) was obtained for samples with an organic-inorganic ratio of 80:20 and a percentage of Silver salt of 5 wt% with respect to the coating. For the coatings prepared by an acid catalyzed process, a good antibacterial activity of the coated films was demonstrated through repeated washings in warm water or in physiological saline solution at room temperature.
Marini M., De Niederhausern S., Iseppi R., Bondi M., Sabia C., Toselli M., et al. (2007). Antibacterial Activity of Plastics Coated with Silver-Doped Organic-Inorganic Hybrid Coatings Prepared by Sol-Gel Processes. BIOMACROMOLECULES, 8(4), 1246-1254 [10.1021/bm060721b].
Antibacterial Activity of Plastics Coated with Silver-Doped Organic-Inorganic Hybrid Coatings Prepared by Sol-Gel Processes.
TOSELLI, MAURIZIO;
2007
Abstract
Silver-doped organic–inorganic hybrid coatings were prepared starting from tetraethoxysilane and α-triethoxysilane terminated poly(ethylene)–block–poly(ethyleneglycole) using the sol–gel process. They were applied as a thin layer (600-1000 nm) to PE and PVC films and the antibacterial activity of the coated films was tested against Gram-negative (Escherichia coli ATCC 25922) and Gram-positive (Staphylococcus aureus ATCC 6538) bacteria. The effect of several parameters (such as organic-inorganic ratio, type of catalyst, time of post-curing, Silver-ion concentration, etc.) was investigated. Measurements at different contact times showed a rapid decrease of the viable count for both the tested strains. The highest antibacterial activity (more than 6 log reduction within 6 hours starting from 106 CFU ml-1) was obtained for samples with an organic-inorganic ratio of 80:20 and a percentage of Silver salt of 5 wt% with respect to the coating. For the coatings prepared by an acid catalyzed process, a good antibacterial activity of the coated films was demonstrated through repeated washings in warm water or in physiological saline solution at room temperature.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.