Phenotypic screening is a powerful approach in neglected tropical diseases drug discovery. Hence, we tested a focused natural naphthoquinone-inspired library against trypanosomatid cells, providing a promising hit compound with a multitarget mechanism of action.
Federica Prati, Maria Laura Bolognesi (2014). PHENOTYPIC HITS IN ANTI-TRYPANOSOMA DRUG DISCOVERY. LA CHIMICA E L'INDUSTRIA, XCVI(5/6), 46-47.
PHENOTYPIC HITS IN ANTI-TRYPANOSOMA DRUG DISCOVERY
PRATI, FEDERICA;BOLOGNESI, MARIA LAURA
2014
Abstract
Phenotypic screening is a powerful approach in neglected tropical diseases drug discovery. Hence, we tested a focused natural naphthoquinone-inspired library against trypanosomatid cells, providing a promising hit compound with a multitarget mechanism of action.File in questo prodotto:
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