NPM1 mutations have been reported to be the most frequent mutations in acute myeloid leukemia (AML). They are associated with a wide spectrum of morphologic subtypes of AML, normal karyotype and FLT3 mutations. The high frequency of NPM1 mutations might provide a suitable marker for monitoring residual disease of AML.
Titolo: | NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukemia. | |
Autore/i: | Palmisano M; GRAFONE, TIZIANA; OTTAVIANI, EMANUELA; TESTONI, NICOLETTA; BACCARANI, MICHELE; MARTINELLI, GIOVANNI | |
Autore/i Unibo: | ||
Anno: | 2007 | |
Rivista: | ||
Digital Object Identifier (DOI): | http://dx.doi.org/10.3324/haematol.11202 | |
Abstract: | NPM1 mutations have been reported to be the most frequent mutations in acute myeloid leukemia (AML). They are associated with a wide spectrum of morphologic subtypes of AML, normal karyotype and FLT3 mutations. The high frequency of NPM1 mutations might provide a suitable marker for monitoring residual disease of AML. | |
Data prodotto definitivo in UGOV: | 2007-10-15 16:03:01 | |
Appare nelle tipologie: | 1.01 Articolo in rivista |
File in questo prodotto:
Eventuali allegati, non sono esposti
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.