In July 1985, a 43-year-old man was found to have polycythaemia vera. The peripheral blood counts were white cell count 14.15x109/l (neutrophils 80%, lymphocytes 14%, monocytes 5%, eosinophils 1%), haemoglobin concentration 24.8 g/dl, haematocrit 0.7, red cell count 8.15x1012/l (neither anisocytosis nor poikilocytosis nor tear-drop poikilocytosis were observed), platelets 234x109/l. As only the erythroid lineage was affected significantly, he was treated with isovolaemic phlebotomy until April 2004. In May 2004, the patient suddenly developed a spastic paraplegia. Nuclear magnetic resonance imaging showed a posterior extradural tumour extending from T3 to T11 (fig 1A, B). The lesion expanded into the vertebral canal, inducing spinal cord compression. The occurrence of either a second neoplasm or a myeloid sarcoma (rare but possible during the clinical course of polycythaemia vera) was considered in the differential diagnosis. After thoracic laminectomy (from T2 to T11) and . . .

Piccaluga PP, Finelli C, Vigna E, Agostinelli C, Bacci F, Paolini S, et al. (2007). Paraplegia due to a paravertebral extramedullary haemopoiesis in a patient with polycythaemia vera. JOURNAL OF CLINICAL PATHOLOGY, 60(5), 581-582.

Paraplegia due to a paravertebral extramedullary haemopoiesis in a patient with polycythaemia vera.

PICCALUGA, PIER PAOLO;FINELLI, CARLO;AGOSTINELLI, CLAUDIO;PAOLINI, STEFANIA;PAPAYANNIDIS, CRISTINA;LATERZA, CLAUDIO;MARTINELLI, GIOVANNI;PILERI, STEFANO;BACCARANI, MICHELE
2007

Abstract

In July 1985, a 43-year-old man was found to have polycythaemia vera. The peripheral blood counts were white cell count 14.15x109/l (neutrophils 80%, lymphocytes 14%, monocytes 5%, eosinophils 1%), haemoglobin concentration 24.8 g/dl, haematocrit 0.7, red cell count 8.15x1012/l (neither anisocytosis nor poikilocytosis nor tear-drop poikilocytosis were observed), platelets 234x109/l. As only the erythroid lineage was affected significantly, he was treated with isovolaemic phlebotomy until April 2004. In May 2004, the patient suddenly developed a spastic paraplegia. Nuclear magnetic resonance imaging showed a posterior extradural tumour extending from T3 to T11 (fig 1A, B). The lesion expanded into the vertebral canal, inducing spinal cord compression. The occurrence of either a second neoplasm or a myeloid sarcoma (rare but possible during the clinical course of polycythaemia vera) was considered in the differential diagnosis. After thoracic laminectomy (from T2 to T11) and . . .
2007
Piccaluga PP, Finelli C, Vigna E, Agostinelli C, Bacci F, Paolini S, et al. (2007). Paraplegia due to a paravertebral extramedullary haemopoiesis in a patient with polycythaemia vera. JOURNAL OF CLINICAL PATHOLOGY, 60(5), 581-582.
Piccaluga PP; Finelli C; Vigna E; Agostinelli C; Bacci F; Paolini S; Papayannidis C; Laterza C; Martinelli G; Pileri SA; Baccarani M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/46789
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