Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.
Titolo: | The potential of stem cells as an in vitro source of red blood cells for transfusion |
Autore/i: | FRANCO MIGLIACCIO, ANNA RITA; Whitsett, C; Papayannopoulou, T; Sadelain, M. |
Autore/i Unibo: | |
Anno: | 2012 |
Rivista: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.stem.2012.01.001 |
Abstract: | Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena. |
Data stato definitivo: | 2015-11-09T10:07:05Z |
Appare nelle tipologie: | 1.01 Articolo in rivista |
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