Within the developing interface between free radicals and supramolecular chemistry, nitroxides play a special role because they are stable and easy to functionalize. This Focus Review summarizes recent progress in the design and synthesis of paramagnetic host-guest complexes characterized by the presence of a nitroxide label covalently linked to the organic macrocycle. Examples include the synthesis of open-shell, mechanically interlocked molecules (MIMs), such as rotaxanes, in which the dumbbell, the wheel, or both are tagged with nitroxide radicals, and how electron spin resonance (ESR) spectroscopy methods have been used for detecting and identifying the assemblies and for clarifying their structure and properties.
Elisabetta Mezzina, Roberta Manoni, Francesco Romano, Marco Lucarini (2015). Spin-Labelling of Host-Guest Assemblies with Nitroxide Radicals. ASIAN JOURNAL OF ORGANIC CHEMISTRY, 4, 296-310 [10.1002/ajoc.201402286].
Spin-Labelling of Host-Guest Assemblies with Nitroxide Radicals
MEZZINA, ELISABETTA;MANONI, ROBERTA;ROMANO, FRANCESCO;LUCARINI, MARCO
2015
Abstract
Within the developing interface between free radicals and supramolecular chemistry, nitroxides play a special role because they are stable and easy to functionalize. This Focus Review summarizes recent progress in the design and synthesis of paramagnetic host-guest complexes characterized by the presence of a nitroxide label covalently linked to the organic macrocycle. Examples include the synthesis of open-shell, mechanically interlocked molecules (MIMs), such as rotaxanes, in which the dumbbell, the wheel, or both are tagged with nitroxide radicals, and how electron spin resonance (ESR) spectroscopy methods have been used for detecting and identifying the assemblies and for clarifying their structure and properties.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
